Lumidox® II LED Arrays

U.S. Patent No. 11,458,447

Analytical’s patented LED arrays provide wavelength and power specific illumination to samples for photoredox catalysis applications.

Up to 15 different color wavelengths are available*
5 output STAGES (customizeable) with calibration data stored on board**
Available in two Surface Mat styles
Three options for Base configurations
(see the expandable section below: "Learn more about LED Arrays")

Lumidox II LED Arrays are available in up to 15 wavelengths*:
365nm UV, 375nm UV, 385nm UV, 395nm UV, 405nm UV, 420nm-Violet, 445nm-Indigo, 470nm-Blue, 505nm-Cyan, 527nm-Green, 590nm-Amber, 630nm-Red, 660nm-Deep Red, 730nm-IR Infrared and White. Note: LUM2CON controller is required to power LED arrays.

* Most LED arrays (excluding Discovery) are wavelength-specific - only one wavelength per device
** Calibration data is stored onboard (not on the controller), allowing the use of different illuminators with one controller. Controller can only operate 1 device at a time. STAGE settings are NOT user-adjustable and must be configured prior to shipping

Learn more about LED Arrays - Expand

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Surface Mat Styles
Array top surfaces come in two styles, Lens Mat and Diffuse Mat.

Lens Mat Surface

Ultra-clear, molded to fit into the holes of a Para-dox® Reaction Block
Captures nearly all light emitted by the array’s LEDs and directs it into the vials in the reaction block
Chemically inert silicone

Diffuse Mat Surface

Flat surface, making for easy pairing with SLAS footprint apparatus
Can be used for niche applications such as illuminating cell culture flasks, reservoir plates, large scale containers, etc.
Chemically inert silicone

About Array Cooling and Base Options
Lumidox® II LED Arrays can generate a considerable amount of heat at any output stage and therefore need to be cooled. Both Lens Mat and Diffuse Mat style arrays are available with an Active Cooling base, Solid base or Flow-Through base. Each has it’s own specific way of cooling the LEDs in the array and can affect different application situations.

Active Cooling Base:

Self-cooling, no external cooling source required
Fully conforms to SLAS/ANSI standard dimensions
Ideal for lower output applications like cell culture and PCR work (may require special adapter)
Not compatible with tumble stirrers or devices that generate powerful magnetic fields

Solid Base:

External cooling source is required (see Thermal Transfer Deck)
A Thermal Transfer Deck (TTD) is recommended and can be attached to the base when used in conjunction with a recirculating chiller. The TTD can be removed if using a different cooling source, such as a cooling bay
Fully conforms to SLAS/ANSI standards and can be used with cooling baths, plates, or other cooling chamber (if NOT being used with our Thermal Transfer Deck and recirculating liquid chiller)
Ideal for applications requiring high output - up to nearly 3x more radiometric power output than Active Base arrays

NEW! Flow-Through Base:

Provides the most optimal cooling efficiency for LED arrays
Direct connection to recirculating liquid chiller (required). Cooled liquid flows through the array base itself (no need for Thermal Transfer Deck)
Ideal for applications requiring high output - up to nearly 3x more radiometric power output than Active Base arrays
Light Weight – improved usability with orbital shakers due to lower overall mass
Shorter overall height than active base array – offers improved compatibility with tumble stirrers (less distance between stirrer and sample)

Note: All LED arrays can operate in an incubator at 37ºC, 95% humidity

For added protection, each device has a built-in thermal cutoff switch that, in case of overheating, will automatically shut down the unit. The trip temperature for Solid Base and Flow-thru Base Arrays is 95°C, and will reset when cooled to 65°C. Active Cooling Base Arrays will shut down if their temperature exceeds 75°C. They will reset once they have cooled to 45°C.

Note: Active Cooling Base arrays are not compatible with strong magnetic fields such as those found in most tumble stirrers due to interference with the cooling fans.

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Lumidox® II STAGES
By default, all Lumidox II devices are factory calibrated with 5 discrete linearly stepped output STAGES... Expand

Lumidox® II STAGE Selection
By default, all Lumidox II devices are factory calibrated with 5 discrete linearly stepped output STAGES (Example 1, below). STAGE 1 output is the least radiometric power while STAGE 5 output is the most. For LED arrays with Active Cooling Stage bases, STAGE 5 thermal dissipation requirements are configured to an appropriate level for each device's built-in thermal satisfaction abilities. STAGE 5 defaults for Passive (solid) Base Arrays are tuned to be thermally satisfied with an average powered chiller in thermal contact with the array base. STAGES are calibrated to nearest whole number of radiant flux, and displayed in milliwatts (mW).

Analytical Sales & Services offers custom tuned stages to meet specific and unique requirements. A user, for example, may have a more sophisticated cooling mechanism and require an array tuned for maximum light output. In this scenario, Analytical would tune the upper STAGES to higher levels than typically thermally controllable by standard users (Example 2). In another example, a user may have a need for a tighter resolution of STAGES (Example 3).

For custom STAGE settings, please contact Analytical Sales & Services before ordering. Note: STAGES may only be calibrated at the time of shipment.

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96-Well LED Arrays with Lens Mat and Active Cooling Base Radiant Flux Values per STAGE \| Irradiance Values per STAGE Example (typical values*)
		Stage 1 Radiant Flux		Stage 2 Radiant Flux		Stage 3 Radiant Flux		Stage 4 Radiant Flux		Stage 5 Radiant Flux
Catalog No.	Wavelength	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)
LUM296LA365	UV365	25	2.4	55	5.3	80	7.7	105	10.1	135	13.0
LUM296LA375	UV375	25	2.4	50	4.8	75	7.2	110	10.6	140	13.4
LUM296LA385	UV385	30	2.9	65	6.2	100	9.6	145	13.9	165	15.8
LUM296LA395	UV395	30	2.9	65	6.2	105	10.1	140	13.4	170	16.3
LUM296LA405	UV405	25	2.4	60	5.8	90	8.6	125	12	160	15.4
LUM296LA420	420-Violet	30	2.9	60	5.8	90	8.6	120	11.5	150	14.4
LUM296LA445	445-Indigo	50	4.8	100	9.6	150	14.4	195	18.7	240	23.0
LUM296LA470	470-Blue	45	4.3	95	9.1	140	13.4	180	17.3	220	21.1
LUM296LA505	505-Cyan	35	3.4	65	6.2	90	8.6	115	11.0	135	13.0
LUM296LA527	527-Green	25	2.4	55	5.3	80	7.7	100	9.6	110	10.6
LUM296LA590	590-Amber	40	3.8	75	7.2	115	11.0	150	14.4	180	17.3
LUM296LA630	630-Red	30	2.9	55	5.3	85	8.2	115	11.0	145	13.9
LUM296LA660	660-Deep Red	40	3.8	70	6.7	105	10.1	140	13.4	170	16.3
LUM296LA730	IR730	35	3.4	65	6.2	95	9.1	125	12.0	155	14.9
LUM296LAWHT	White	50	4.8	100	9.6	150	14.4	200	19.2	300	28.8

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96-Well LED Arrays with Lens Mat and Active Cooling Base Radiant Flux Values per STAGE \| Irradiance Values per STAGE Example (typical values*)
		Irradiance at Surface of Each Lens Mat Tip
		Stage 1	Stage 2	Stage 3	Stage 4	Stage 5
Catalog No.	Wavelength	(mW/cm2)	(mW/cm2)	(mW/cm2)	(mW/cm2)	(mW/cm2)
LUM296LA365	UV365	125	280	405	535	690
LUM296LA375	UV375	125	255	380	560	715
LUM296LA385	UV385	155	330	510	470	840
LUM296LA395	UV395	155	330	535	715	865
LUM296LA405	UV405	125	305	460	635	815
LUM296LA420	420-Violet	155	305	460	610	765
LUM296LA445	445-Indigo	255	510	765	995	1225
LUM296LA470	470-Blue	230	485	715	915	1120
LUM296LA505	505-Cyan	180	330	460	585	690
LUM296LA527	527-Green	130	280	410	510	560
LUM296LA590	590-Amber	205	380	585	765	915
LUM296LA630	630-Red	155	280	435	585	740
LUM296LA660	660-Deep Red	205	355	535	715	865
LUM296LA730	IR730	180	330	485	635	790
LUM296LAWHT	White	255	510	765	1020	1530

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96-Well LED Arrays with Lens Mat and Solid Base Radiant Flux Values per STAGE \| Irradiance Values per STAGE Example (typical values*)
		Stage 1 Radiant Flux		Stage 2 Radiant Flux		Stage 3 Radiant Flux		Stage 4 Radiant Flux		Stage 5 Radiant Flux
Catalog No.	Wavelength	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)	Per well (mW)	Total (W)
LUM296LS365	UV365	55	5.3	110	10.8	165	15.8	215	20.6	395	37.9
LUM296LS375	UV375	50	4.8	125	12.0	160	15.4	220	21.1	275	26.4
LUM296LS385	UV385	65	6.2	145	13.9	210	20.2	350	33.6	425	40.8
LUM296LS395	UV395	65	6.2	135	13.0	250	24.0	330	31.7	510	49.0
LUM296LS405	UV405	70	6.7	145	13.9	200	19.2	285	27.4	435	41.8
LUM296LA420	420-Violet	60	5.8	120	11.5	180	17.3	235	22.6	340	32.6
LUM296LS445	445-Indigo	100	9.6	195	18.7	285	27.4	370	35.5	515	49.4
LUM296LS470	470-Blue	95	9.1	190	18.2	275	26.4	350	33.6	500	48.0
LUM296LS505	505-Cyan	60	5.8	115	11.0	165	15.8	210	20.2	290	27.8
LUM296LS527	527-Green	55	5.3	100	9.6	140	13.4	175	16.8	215	20.6
LUM296LS590	590-Amber	75	7.2	145	13.9	210	20.2	295	28.3	380	36.5
LUM296LS630	630-Red	55	5.3	115	11.0	175	16.8	230	22.1	330	31.7
LUM296LS660	660-Deep Red	70	6.7	140	13.4	205	19.7	275	26.4	400	38.4
LUM296LS730	IR730	65	6.2	125	12.0	185	17.8	245	23.5	365	35.0
LUM296LSWHT	White	70	6.7	140	13.4	210	20.2	275	26.4	400	38.4

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96-Well LED Arrays with Lens Mat and Solid Base Radiant Flux Values per STAGE \| Irradiance Values per STAGE Example (typical values*)
		Irradiance at Surface of Each Lens Mat Tip
		Stage 1	Stage 2	Stage 3	Stage 4	Stage 5
Catalog No.	Wavelength	(mW/cm2)	(mW/cm2)	(mW/cm2)	(mW/cm2)	(mW/cm2)
LUM296LS365	UV365	280	560	840	1095	2010
LUM296LS375	UV375	255	635	815	1120	1400
LUM296LS385	UV385	330	740	1070	1785	2165
LUM296LS395	UV395	330	690	1275	1680	2595
LUM296LS405	UV405	355	740	1020	1450	2215
LUM296LS420	420-Violet	305	610	915	1195	1730
LUM296LS445	445-Indigo	510	995	1455	1885	2625
LUM296LS470	470-Blue	485	970	1400	1785	2545
LUM296LS505	505-Cyan	305	585	840	1070	1475
LUM296LS527	527-Green	280	510	715	890	1095
LUM296LS590	590-Amber	380	740	1070	1500	1935
LUM296LS630	630-Red	280	585	890	1170	1680
LUM296LS660	660-Deep Red	355	715	1045	1400	2035
LUM296LS730	IR730	330	635	940	1250	1860
LUM296LSWHT	White	355	715	1070	1400	2035

*For reference only. Typical values subject to change.

Each Lumidox® II Array comes with it's own calibration document

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Typical Spectral Characterization

UV Wavelengths
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Visible Wavelengths
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Broad Spectrum Wavelengths
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Infrared Wavelengths
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Typical Spectral Characterization

UV Wavelengths
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Visible Wavelengths
Expand

Broad Spectrum Wavelengths
Expand

Infrared Wavelengths
Expand

UV Wavelengths

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Typical Spectral Characterization

UV Wavelengths
Expand

Visible Wavelengths
Expand

Broad Spectrum Wavelengths
Expand

Infrared Wavelengths
Expand

Visible Wavelengths

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Typical Spectral Characterization

UV Wavelengths
Expand

Visible Wavelengths
Expand

Broad Spectrum Wavelengths
Expand

Infrared Wavelengths
Expand

Broad Spectrum Wavelengths

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Typical Spectral Characterization

UV Wavelengths
Expand

Visible Wavelengths
Expand

Broad Spectrum Wavelengths
Expand

Infrared Wavelengths
Expand

Infrared Wavelengths

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Frequently Asked Questions

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I need to change my output levels for each stage. Can I do this remotely?

Yes, please contact engineering@analytical-sales.com for assistance. We will be able to walk you through the process. Please be sure to navigate to the "Additional Information" tab on our Lumidox controller webpage ahead of time, and download the firmware update files. Within that folder will be an executable file named GUI5R7529.exe. This is the GUI that we will utilize to make the changes to the array. Please contact your IT department if the file is blocked. You will also require a the USB Cable that was provided with your controller.

Can you support my need for pulsing of the LED arrays?

We do provide some Python scripts for convenience. These downloadable files can be found under the “Additional Information” tab of the LUM2CON product page. Please note that the use of scripts for the Lumidox controller is experimental and not a supported commercial feature.

Are the Lumidox® II LED arrays compatible with well plates?

Yes, our LED arrays are compatible with any SLAS/ANSI microplate, well plate, cell culture plate, etc. Please note that the use of a well plate adapter may be required for proper alignment.

What can cause the lens or diffuse mats to swell during operation?

The silicone mat may stretch or expand at high temperatures. This is normal, and the mat will return to it’s original size and shape upon cooling down. Avoid removing a 96-well Para-dox reaction block from a lens mat Lumidox array while the system is at high temperature due to potential damage to the silicone lens mat. Allow the array to cool below a safe handling temperature (typically below 45°C).

Can the Lumidox II be integrated with automation systems?

Our Lumidox units are easy to integrate with automation systems, as they were designed with this intention in mind. The serial commands themselves plus some sample Python files can be downloaded from the "Additional Information" tab on our Lumidox controller page. Note that these features are currently experimental, and not yet officially supported. The available commands in Lumidox Controller II – Serial Commands guide should cover all of the tasks needed to integrate and fire the units with your automation platform. Analytical also has "extension" cord sets available to extend the distance the array can be from the controller.

Can the light intensity of the Lumidox® II be reduced?

Yes. Placing thick plates of glass (preferably quartz) between the light source and the plate will increase the distance between the plates and the Lumidox® II, thereby reducing the amount of light reaching the samples. If your samples are still getting too much light, the array can be sent to Analytical to be re-calibrated for lower output.

What is the difference between a Lens Mat and a Diffuse Mat?

A Lens Mat
- Specifically molded to fit a Para-dox® Reaction Block.
- Reaction block captures nearly all light emitted by the array’s LEDs.
- Directs light into the vials, minimizing incident light escape.

A Diffuse Mat
- Adheres to the SLAS footprint,
- Generates diffuse lighting,
- Can be used for niche applications, such as illuminating cell culture flasks and reservoir plates.

Why does my GEN1 Array read “GEN1” instead of displaying the wavelength field?

This is normal when using a GEN1 array with an adapter. GEN1 units have nowhere to store any calibration or wavelength data on the array. The adapters for the GEN1 Base Array are universal so they cannot populate the wavelength field with any numerical values.

Why is my solid base array overheating even though I’m using a chiller?

There are several potential sources for overheating of the solid base array:

An underpowered chiller. Off-brand chillers may lack the required cooling capacity (measured in Watts) to remove all of the heat that the Lumidox array is producing. The chiller that Analytical sells has a capacity of 230 W at 20°C.
Inadequate heat transfer between the TTD and Lumidox array. If the Lumidox array was received with a TTD attached, the screws which hold the two together may have come loose in transit. If the TTD was purchased after the fact, screws and some form of thermal interface material are needed to provide optimal heat transfer.
High coolant temperature. If the temperature of the coolant is too high, insufficient heat may be transferred from the array. Switching to a water/glycol blend may protect against freezing.
Obstructed coolant flow. It is possible that something may have blocked the flow of coolant within the TTD. To check, hook up only one tube/hose and observe the flow of coolant into a sink or container. It is also possible that the pump within the chiller may be underpowered. The chiller that Analytical sells has a capacity of 2 L/min @ 965 mbar.

Which Base Array would be recommended for improved magnetic stirring?

Our Solid Base Array coupled with our Thermal Transfer Deck (TTD),
Our Flow-Through Base Array (best option).

Can the TCube Edge Chiller cool multiple daisy-chained TTDs? If so, how many can be daisy chained?

Yes, the TCube Edge Chiller has the capacity required to cool multiple thermal loads connected in series. Analytical is unable to provide any general specifications since the performance of the chiller in this application is highly dependent on what is being cooled and how much heat is being removed. Analytical suggests using the TTD+ and the Daisy-Chain Connector for easy daisy chaining. Daisy-chaining any TTD will always result in some sort of temperature gradient as the coolant moves through the system and picks up/removes heat.

Would increasing the distance between a 96-well plate and the light source decrease light intensity?

Yes, the best way to do this would be to add thick plates of glass between the light source and your plate. Quartz is preferred, but regular borosilicate may be OK for wavelengths above 405nm.

Does Analytical offer an additional diffuse mat with lower light intensity?

Users have the option of selecting a diffuse mat for their arrays which offer about ~5% lower radiometric/light output over the lens mat. No additional diffuse mat is available at this time, however Analytical can provide custom calibration if lower light intensity is needed.

Is there any way to tune the LEDs to a particular wavelength?

While tuning the LEDs to an exact wavelength is not possible, Analytical may be able to suggest LEDs that provide appreciable power at non-peak wavelengths.

Do you have readings of the temperature at the top of the mats?

The silicone lens mat is non heat conductive. At this time we do not have readings at the top of the lens mat. Most of the time users are concerned about reactor temperature.

Is the lens mat heat conductive?

The silicone lens mat is non heat conductive.

Does the lens mat provide homogeneous illumination of the bottom of a 96 well plate?

Yes, but the plate must be carefully aligned with the lens mat. Custom adapters have been created for this purpose; you can find them on this page as well as some examples.

Do you have data on the irradiance (mW/cm^2) at the level of the well plate bottom?

There is irradiance data in mW/cm^2 taken from the tip of the protrusions on the lens mat. That data can be located HERE by expanding the STAGES section, then clicking on Irradiance Values per STAGE. Lower values can be achieved if needed. Analytical has done many custom calibrations where we give readings from the bottom of the wells in the plate. One or two sample plates would need to be sent to Analytical to custom calibrate exactly to your setup.

Do you have an LED controller that can control multiple devices simultaneously?

Not currently, but plans for such a controller are in the works.

Can the individual LEDs or sections of LED array (rows or columns) be programmed separately for power and temporal profiles beyond the countdown timer?

No. All the LEDs on the array can only be programmed together. However, there are some downloadable files on this page under the “Additional Information” tab that can allow for a for more customizable functions. One of these files offers a pulse function.

Can Lumidox® Gen II Arrays be used in cell culture incubators?

Yes. If you are unsure if the incubators would be appropriate for you environment, contact customerservice@analytical-sales.com and we can confirm with the engineering team.

Can I program the LEDs myself? Can I turn on/off individual LEDs?

No. The LEDs can only be turned on or off all at once. However, Analytical can calibrate the LEDs to one of five distinct stages for your desired power output.

Can Lumidox® Gen II Arrays work at temperatures below 0°C?

Yes, Lumidox II Arrays can be chilled to -30C° and will still work as intended.

Can a reaction block, together with a LED array and Thermal Transfer Deck be used with a magnetic stirrer or mechanical shaker?

The unit can be used with a mechanical shaker. However, due to the assembled unit's thickness, success with a magnetic stirrer varies. Some customers are able to use it, while for others the magnetic field is not powerful enough to penetrate the total thickness of aluminum of the Thermal Transfer Deck cooling base.<br> If you have a fairly robust magnetic stirrer, you can certainly give it a try. Keep in mind, only solid base LED arrays can be used with a magnetic stirrer, as there are no fans or other components (as in active base) that would be negatively affected by the magnetic field of the stirrer.

What is the lifetime of the LEDs?

The LEDs have an approximate lifetime of 50,000 hours when operating under normal, ambient conditions.

What are STAGES?

Stages are radiometric output levels, of varying intensity, selectable by the front mounted controller dial.

My unit turned off, is it broken?

Gen II arrays contain a resettable fuse. If internal temperatures surpass this fuse, the unit will temporarily be prevented from illuminating. Power cycle the device and wait for the array to cool before operating. For Solid Base Arrays, the cutoff temperature is 95°C and will reset when cooled to 65°C. For Active Cooling Base Arrays, the cutoff is 75°C and will reset at 45°C. LumLamp units contain a single use thermal protection fuse. Fuse repair is not possible in LumLamp units.

Who is the manufacturer of the LEDs?

We do not disclose this information, but can confirm that they are sourced from high quality manufacturers, and binned together for uniformity.

Do you offer light and heat mapping of the arrays?

Not at this time.

Is there a way to continuously sweep the light intensity?

This is not currently possible as a custom option.

Do you offer custom array calibration?

If you know what your optical power requirements are for a given wavelength, we can custom tune the units to your desired 5 stages.

Do I need an external cooling system for use with the active cooling base arrays?

The active cooling base arrays have both fans, and a heat sink, so they can cool themselves.

Do I need an external cooling system for use with the solid base arrays?

The solid base (passive) arrays do require an external cooling source such as a chiller/cooling plate or dry cooling bath.

How efficient are the cooling fans on the active cooling base?

The efficiency of the cooling system is HIGHLY variable based on LED wavelength and type of reaction being catalyzed. As a general guide for informational purposes only, for the 5 default power levels, if starting out at ~20°C you can expect stage 1 to maintain a reactor block temperature of ~22°C, stage 2 to ~27°C, stage 3 to ~35°C, stage 4 to ~46°C, and stage 5 to ~60°C. For additional cooling capability, we suggest using a chiller with a cooling plate (utilizing a liquid coolant) on top of your reactor block.

Are you able to modulate intensity?

Yes, modulating the output intensity is achieved by turning the front mounted dial to the desired output stage.

What is the power/output difference between Gen I and Gen II arrays?

See Gen I vs Gen II Array Comparison

What are the spectral outputs of the different wavelengths?

Typical spectral outputs can be found here. However, with each array or LumLamp, we provide a unique calibration document that notes this information, specific to the device. See an example of this document

What are the power and output of each LED, and the LED array as a whole?

See Stages and Radiant Flux Data Charts

I’m trying to match the J/cm² values from a research paper. Can you help me determine how long to expose my samples?

Click here for Analytical's Intensity Conversion Chart

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