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Photoredox Catalysis & Parallel Synthesis

Lumidox® II LED Arrays

U.S. Patent No. 11,458,447
Analytical’s patented LED arrays provide wavelength and power specific illumination to samples for photoredox catalysis applications.
  • Up to 15 different color wavelengths are available*
  • 5 output STAGES (customizeable) with calibration data stored on board**
  • Available in two Surface Mat styles
  • Three options for Base configurations
    (see the expandable section below: "Learn more about LED Arrays")
Lumidox II LED Arrays are available in up to 15 wavelengths*:
365nm UV, 375nm UV, 385nm UV, 395nm UV, 405nm UV, 420nm-Violet, 445nm-Indigo, 470nm-Blue, 505nm-Cyan, 527nm-Green, 590nm-Amber, 630nm-Red, 660nm-Deep Red, 730nm-IR Infrared and White. Note: LUM2CON controller is required to power LED arrays.
* Most LED arrays (excluding Discovery) are wavelength-specific - only one wavelength per device
** Calibration data is stored onboard (not on the controller), allowing the use of different illuminators with one controller. Controller can only operate 1 device at a time. STAGE settings are NOT user-adjustable and must be configured prior to shipping

Learn more about LED Arrays - Expand

Surface Mat Styles
Array top surfaces come in two styles, Lens Mat and Diffuse Mat.

Lens Mat Surface
  • Ultra-clear, molded to fit into the holes of a Para-dox® Reaction Block
  • Captures nearly all light emitted by the array’s LEDs and directs it into the vials in the reaction block
  • Chemically inert silicone
Diffuse Mat Surface
  • Flat surface, making for easy pairing with SLAS footprint apparatus
  • Can be used for niche applications such as illuminating cell culture flasks, reservoir plates, large scale containers, etc.
  • Chemically inert silicone



About Array Cooling and Base Options
Lumidox® II LED Arrays can generate a considerable amount of heat at any output stage and therefore need to be cooled. Both Lens Mat and Diffuse Mat style arrays are available with an Active Cooling base, Solid base or Flow-Through base. Each has it’s own specific way of cooling the LEDs in the array and can affect different application situations.

Active Cooling Base:
  • Self-cooling, no external cooling source required
  • Fully conforms to SLAS/ANSI standard dimensions
  • Ideal for lower output applications like cell culture and PCR work (may require special adapter)
  • Not compatible with tumble stirrers or devices that generate powerful magnetic fields

Solid Base:
  • External cooling source is required (see Thermal Transfer Deck)
  • A Thermal Transfer Deck (TTD) is recommended and can be attached to the base when used in conjunction with a recirculating chiller. The TTD can be removed if using a different cooling source, such as a cooling bay
  • Fully conforms to SLAS/ANSI standards and can be used with cooling baths, plates, or other cooling chamber (if NOT being used with our Thermal Transfer Deck and recirculating liquid chiller)
  • Ideal for applications requiring high output - up to nearly 3x more radiometric power output than Active Base arrays

NEW! Flow-Through Base:
  • Provides the most optimal cooling efficiency for LED arrays
  • Direct connection to recirculating liquid chiller (required). Cooled liquid flows through the array base itself (no need for Thermal Transfer Deck)
  • Ideal for applications requiring high output - up to nearly 3x more radiometric power output than Active Base arrays
  • Light Weight – improved usability with orbital shakers due to lower overall mass
  • Shorter overall height than active base array – offers improved compatibility with tumble stirrers (less distance between stirrer and sample)

Note: All LED arrays can operate in an incubator at 37ºC, 95% humidity

For added protection, each device has a built-in thermal cutoff switch that, in case of overheating, will automatically shut down the unit. The trip temperature for Solid Base and Flow-thru Base Arrays is 95°C, and will reset when cooled to 65°C. Active Cooling Base Arrays will shut down if their temperature exceeds 75°C. They will reset once they have cooled to 45°C.

Note: Active Cooling Base arrays are not compatible with strong magnetic fields such as those found in most tumble stirrers due to interference with the cooling fans.




Lumidox® II STAGES
By default, all Lumidox II devices are factory calibrated with 5 discrete linearly stepped output STAGES... Expand

Lumidox® II STAGE Selection
By default, all Lumidox II devices are factory calibrated with 5 discrete linearly stepped output STAGES (Example 1, below). STAGE 1 output is the least radiometric power while STAGE 5 output is the most. For LED arrays with Active Cooling Stage bases, STAGE 5 thermal dissipation requirements are configured to an appropriate level for each device's built-in thermal satisfaction abilities. STAGE 5 defaults for Passive (solid) Base Arrays are tuned to be thermally satisfied with an average powered chiller in thermal contact with the array base. STAGES are calibrated to nearest whole number of radiant flux, and displayed in milliwatts (mW).

Analytical Sales & Services offers custom tuned stages to meet specific and unique requirements. A user, for example, may have a more sophisticated cooling mechanism and require an array tuned for maximum light output. In this scenario, Analytical would tune the upper STAGES to higher levels than typically thermally controllable by standard users (Example 2). In another example, a user may have a need for a tighter resolution of STAGES (Example 3).



For custom STAGE settings, please contact Analytical Sales & Services before ordering. Note: STAGES may only be calibrated at the time of shipment.


96-Well LED Arrays with Lens Mat and Active Cooling Base

Radiant Flux Values per STAGE | Irradiance Values per STAGE
Example (typical values*)
Stage 1 Radiant FluxStage 2 Radiant FluxStage 3 Radiant FluxStage 4 Radiant FluxStage 5 Radiant Flux
Catalog No.WavelengthPer well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)
LUM296LA365UV365252.4555.3807.710510.113513.0
LUM296LA375UV375252.4504.8757.211010.614013.4
LUM296LA385UV385302.9656.21009.614513.916515.8
LUM296LA395UV395302.9656.210510.114013.417016.3
LUM296LA405UV405252.4605.8908.61251216015.4
LUM296LA420420-Violet302.9605.8908.612011.515014.4
LUM296LA445445-Indigo504.81009.615014.419518.724023.0
LUM296LA470470-Blue454.3959.114013.418017.322021.1
LUM296LA505505-Cyan353.4656.2908.611511.013513.0
LUM296LA527527-Green252.4555.3807.71009.611010.6
LUM296LA590590-Amber403.8757.211511.015014.418017.3
LUM296LA630630-Red302.9555.3858.211511.014513.9
LUM296LA660660-Deep Red403.8706.710510.114013.417016.3
LUM296LA730IR730353.4656.2959.112512.015514.9
LUM296LAWHTWhite504.81009.615014.420019.230028.8


96-Well LED Arrays with Lens Mat and Active Cooling Base

Radiant Flux Values per STAGE | Irradiance Values per STAGE
Example (typical values*)
Irradiance at Surface of Each Lens Mat Tip
Stage 1Stage 2Stage 3Stage 4Stage 5
Catalog No.Wavelength(mW/cm2)(mW/cm2)(mW/cm2)(mW/cm2)(mW/cm2)
LUM296LA365UV365125280405535690
LUM296LA375UV375125255380560715
LUM296LA385UV385155330510470840
LUM296LA395UV395155330535715865
LUM296LA405UV405125305460635815
LUM296LA420420-Violet155305460610765
LUM296LA445445-Indigo2555107659951225
LUM296LA470470-Blue2304857159151120
LUM296LA505505-Cyan180330460585690
LUM296LA527527-Green130280410510560
LUM296LA590590-Amber205380585765915
LUM296LA630630-Red155280435585740
LUM296LA660660-Deep Red205355535715865
LUM296LA730IR730180330485635790
LUM296LAWHTWhite25551076510201530


96-Well LED Arrays with Lens Mat and Solid Base

Radiant Flux Values per STAGE | Irradiance Values per STAGE
Example (typical values*)
Stage 1 Radiant FluxStage 2 Radiant FluxStage 3 Radiant FluxStage 4 Radiant FluxStage 5 Radiant Flux
Catalog No.WavelengthPer well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)Per well (mW)Total (W)
LUM296LS365UV365555.311010.816515.821520.639537.9
LUM296LS375UV375504.812512.016015.422021.127526.4
LUM296LS385UV385656.214513.921020.235033.642540.8
LUM296LS395UV395656.213513.025024.033031.751049.0
LUM296LS405UV405706.714513.920019.228527.443541.8
LUM296LA420420-Violet605.812011.518017.323522.634032.6
LUM296LS445445-Indigo1009.619518.728527.437035.551549.4
LUM296LS470470-Blue959.119018.227526.435033.650048.0
LUM296LS505505-Cyan605.811511.016515.821020.229027.8
LUM296LS527527-Green555.31009.614013.417516.821520.6
LUM296LS590590-Amber757.214513.921020.229528.338036.5
LUM296LS630630-Red555.311511.017516.823022.133031.7
LUM296LS660660-Deep Red706.714013.420519.727526.440038.4
LUM296LS730IR730656.212512.018517.824523.536535.0
LUM296LSWHTWhite706.714013.421020.227526.440038.4


96-Well LED Arrays with Lens Mat and Solid Base

Radiant Flux Values per STAGE | Irradiance Values per STAGE
Example (typical values*)
Irradiance at Surface of Each Lens Mat Tip
Stage 1Stage 2Stage 3Stage 4Stage 5
Catalog No.Wavelength(mW/cm2)(mW/cm2)(mW/cm2)(mW/cm2)(mW/cm2)
LUM296LS365UV36528056084010952010
LUM296LS375UV37525563581511201400
LUM296LS385UV385330740107017852165
LUM296LS395UV395330690127516802595
LUM296LS405UV405355740102014502215
LUM296LS420420-Violet30561091511951730
LUM296LS445445-Indigo510995145518852625
LUM296LS470470-Blue485970140017852545
LUM296LS505505-Cyan30558584010701475
LUM296LS527527-Green2805107158901095
LUM296LS590590-Amber380740107015001935
LUM296LS630630-Red28058589011701680
LUM296LS660660-Deep Red355715104514002035
LUM296LS730IR73033063594012501860
LUM296LSWHTWhite355715107014002035

*For reference only. Typical values subject to change.

Each Lumidox® II Array comes with it's own calibration document





Typical Spectral Characterization
UV Wavelengths
Expand
Visible Wavelengths
Expand
Broad Spectrum Wavelengths
Expand
Infrared Wavelengths
Expand

Typical Spectral Characterization
UV Wavelengths
Expand
Visible Wavelengths
Expand
Broad Spectrum Wavelengths
Expand
Infrared Wavelengths
Expand
UV Wavelengths



Typical Spectral Characterization
UV Wavelengths
Expand
Visible Wavelengths
Expand
Broad Spectrum Wavelengths
Expand
Infrared Wavelengths
Expand
Visible Wavelengths



Typical Spectral Characterization
UV Wavelengths
Expand
Visible Wavelengths
Expand
Broad Spectrum Wavelengths
Expand
Infrared Wavelengths
Expand
Broad Spectrum Wavelengths



Typical Spectral Characterization
UV Wavelengths
Expand
Visible Wavelengths
Expand
Broad Spectrum Wavelengths
Expand
Infrared Wavelengths
Expand
Infrared Wavelengths


Frequently Asked Questions

- Expand Collapse
I need to change my output levels for each stage. Can I do this remotely?
Yes, please contact engineering@analytical-sales.com for assistance. We will be able to walk you through the process. Please be sure to navigate to the "Additional Information" tab on our Lumidox controller webpage ahead of time, and download the firmware update files. Within that folder will be an executable file named GUI5R7529.exe. This is the GUI that we will utilize to make the changes to the array. Please contact your IT department if the file is blocked. You will also require a the USB Cable that was provided with your controller.
Can you support my need for pulsing of the LED arrays?
We do provide some Python scripts for convenience. These downloadable files can be found under the “Additional Information” tab of the LUM2CON product page. Please note that the use of scripts for the Lumidox controller is experimental and not a supported commercial feature.
Are the Lumidox® II LED arrays compatible with well plates?
Yes, our LED arrays are compatible with any SLAS/ANSI microplate, well plate, cell culture plate, etc. Please note that the use of a well plate adapter may be required for proper alignment.
What can cause the lens or diffuse mats to swell during operation?
The silicone mat may stretch or expand at high temperatures. This is normal, and the mat will return to it’s original size and shape upon cooling down. Avoid removing a 96-well Para-dox reaction block from a lens mat Lumidox array while the system is at high temperature due to potential damage to the silicone lens mat. Allow the array to cool below a safe handling temperature (typically below 45°C).
Can the Lumidox II be integrated with automation systems?
Our Lumidox units are easy to integrate with automation systems, as they were designed with this intention in mind.The serial commands themselves plus some sample Python files can be downloaded from the "Additional Information" tab on our Lumidox controller page. Note that these features are currently experimental, and not yet officially supported.The available commands in Lumidox Controller II – Serial Commands guide should cover all of the tasks needed to integrate and fire the units with your automation platform. Analytical also has "extension" cord sets available to extend the distance the array can be from the controller.
Can the light intensity of the Lumidox® II be reduced?
Yes. Placing thick plates of glass (preferably quartz) between the light source and the plate will increase the distance between the plates and the Lumidox® II, thereby reducing the amount of light reaching the samples.If your samples are still getting too much light, the array can be sent to Analytical to be re-calibrated for lower output.
What is the difference between a Lens Mat and a Diffuse Mat?
  • A Lens Mat
    • Specifically molded to fit a Para-dox® Reaction Block.
    • Reaction block captures nearly all light emitted by the array’s LEDs.
    • Directs light into the vials, minimizing incident light escape.
  • A Diffuse Mat
    • Adheres to the SLAS footprint,
    • Generates diffuse lighting,
    • Can be used for niche applications, such as illuminating cell culture flasks and reservoir plates.
Why does my GEN1 Array read “GEN1” instead of displaying the wavelength field?
This is normal when using a GEN1 array with an adapter. GEN1 units have nowhere to store any calibration or wavelength data on the array. The adapters for the GEN1 Base Array are universal so they cannot populate the wavelength field with any numerical values.
Why is my solid base array overheating even though I’m using a chiller?
There are several potential sources for overheating of the solid base array:
  • An underpowered chiller. Off-brand chillers may lack the required cooling capacity (measured in Watts) to remove all of the heat that the Lumidox array is producing. The chiller that Analytical sells has a capacity of 230 W at 20°C.
  • Inadequate heat transfer between the TTD and Lumidox array. If the Lumidox array was received with a TTD attached, the screws which hold the two together may have come loose in transit. If the TTD was purchased after the fact, screws and some form of thermal interface material are needed to provide optimal heat transfer.
  • High coolant temperature. If the temperature of the coolant is too high, insufficient heat may be transferred from the array. Switching to a water/glycol blend may protect against freezing.
  • Obstructed coolant flow. It is possible that something may have blocked the flow of coolant within the TTD. To check, hook up only one tube/hose and observe the flow of coolant into a sink or container. It is also possible that the pump within the chiller may be underpowered. The chiller that Analytical sells has a capacity of 2 L/min @ 965 mbar.
Which Base Array would be recommended for improved magnetic stirring?
  • Our Solid Base Array coupled with our Thermal Transfer Deck (TTD),
  • Our Flow-Through Base Array (best option).
Can the TCube Edge Chiller cool multiple daisy-chained TTDs? If so, how many can be daisy chained?
Yes, the TCube Edge Chiller has the capacity required to cool multiple thermal loads connected in series. Analytical is unable to provide any general specifications since the performance of the chiller in this application is highly dependent on what is being cooled and how much heat is being removed. Analytical suggests using the TTD+ and the Daisy-Chain Connector for easy daisy chaining. Daisy-chaining any TTD will always result in some sort of temperature gradient as the coolant moves through the system and picks up/removes heat. 
I am using a Lumidox® Gen I Array. Where can I find data sheets to get the radiant flux values for the amperage that I am using?
The data sheets for the radiant flux are located on this page and this page. Both data sheets can be found under the “Additional Information” tab.
Would increasing the distance between a 96-well plate and the light source decrease light intensity?
Yes, the best way to do this would be to add thick plates of glass between the light source and your plate. Quartz is preferred, but regular borosilicate may be OK for wavelengths above 405nm.
Does Analytical offer an additional diffuse mat with lower light intensity?
Users have the option of selecting a diffuse mat for their arrays which offer about ~5% lower radiometric/light output over the lens mat. No additional diffuse mat is available at this time, however Analytical can provide custom calibration if lower light intensity is needed.
Is there any way to tune the LEDs to a particular wavelength?
While tuning the LEDs to an exact wavelength is not possible, Analytical may be able to suggest LEDs that provide appreciable power at non-peak wavelengths.
Do you have readings of the temperature at the top of the mats?
The silicone lens mat is non heat conductive. At this time we do not have readings at the top of the lens mat. Most of the time users are concerned about reactor temperature.
Is the lens mat heat conductive?
The silicone lens mat is non heat conductive.
Does the lens mat provide homogeneous illumination of the bottom of a 96 well plate?
Yes, but the plate must be carefully aligned with the lens mat. Custom adapters have been created for this purpose; you can find them on this page as well as some examples.
Do you have data on the irradiance (mW/cm^2) at the level of the well plate bottom?
There is irradiance data in mW/cm^2 taken from the tip of the protrusions on the lens mat. That data can be located here by expanding the STAGES section, then clicking on Irradiance Values per STAGE. Lower values can be achieved if needed. Analytical has done many custom calibrations where we give readings from the bottom of the wells in the plate. One or two sample plates would need to be sent to Analytical to custom calibrate exactly to your setup.
Do you have an LED controller that can control multiple devices simultaneously?
Not currently, but plans for such a controller are in the works.
Can the individual LEDs or sections of LED array (rows or columns) be programmed separately for power and temporal profiles beyond the countdown timer?
No. All the LEDs on the array can only be programmed together. However, there are some downloadable files on this page under the “Additional Information” tab that can allow for a for more customizable functions. One of these files offers a pulse function.
Can Lumidox® Gen II Arrays be used in cell culture incubators?
Yes. If you are unsure if the incubators would be appropriate for you environment, contact customerservice@analytical-sales.com and we can confirm with the engineering team.
Can I program the LEDs myself? Can I turn on/off individual LEDs?
No. The LEDs can only be turned on or off all at once. However, Analytical can calibrate the LEDs to one of five distinct stages for your desired power output.
Can Lumidox® Gen II Arrays work at temperatures below 0°C?
Yes, Lumidox II Arrays can be chilled to -30C° and will still work as intended.
Can a reaction block, together with a LED array and Thermal Transfer Deck be used with a magnetic stirrer or mechanical shaker?
The unit can be used with a mechanical shaker. However, due to the assembled unit's thickness, success with a magnetic stirrer varies. Some customers are able to use it, while for others the magnetic field is not powerful enough to penetrate the total thickness of aluminum of the Thermal Transfer Deck cooling base.<br> If you have a fairly robust magnetic stirrer, you can certainly give it a try. Keep in mind, only solid base LED arrays can be used with a magnetic stirrer, as there are no fans or other components (as in active base) that would be negatively affected by the magnetic field of the stirrer.
What is the lifetime of the LEDs?
The LEDs have an approximate lifetime of 50,000 hours when operating under normal, ambient conditions.
What are STAGES?
Stages are radiometric output levels, of varying intensity, selectable by the front mounted controller dial.
My unit turned off, is it broken?
Gen II arrays contain a resettable fuse. If internal temperatures surpass this fuse, the unit will temporarily be prevented from illuminating. Power cycle the device and wait for the array to cool before operating. For Solid Base Arrays, the cutoff temperature is 95°C and will reset when cooled to 65°C. For Active Cooling Base Arrays, the cutoff is 75°C and will reset at 45°C.LumLamp units contain a single use thermal protection fuse. Fuse repair is not possible in LumLamp units.
Who is the manufacturer of the LEDs?
We do not disclose this information, but can confirm that they are sourced from high quality manufacturers, and binned together for uniformity.
Do you offer light and heat mapping of the arrays?
Not at this time.
Is there a way to continuously sweep the light intensity?
This is not currently possible as a custom option.
Do you offer custom array calibration?
If you know what your optical power requirements are for a given wavelength, we can custom tune the units to your desired 5 stages.
Do I need an external cooling system for use with the active cooling base arrays?
The active cooling base arrays have both fans, and a heat sink, so they can cool themselves.
Do I need an external cooling system for use with the solid base arrays?
The solid base (passive) arrays do require an external cooling source such as a chiller/cooling plate or dry cooling bath.
How efficient are the cooling fans on the active cooling base?
The efficiency of the cooling system is HIGHLY variable based on LED wavelength and type of reaction being catalyzed. As a general guide for informational purposes only, for the 5 default power levels, if starting out at ~20°C you can expect stage 1 to maintain a reactor block temperature of ~22°C, stage 2 to ~27°C, stage 3 to ~35°C, stage 4 to ~46°C, and stage 5 to ~60°C. For additional cooling capability, we suggest using a chiller with a cooling plate (utilizing a liquid coolant) on top of your reactor block.
Are you able to modulate intensity?
Yes, modulating the output intensity is achieved by turning the front mounted dial to the desired output stage.
What is the power/output difference between Gen I and Gen II arrays?
What are the spectral outputs of the different wavelengths?
Typical spectral outputs can be found here. However, with each array or LumLamp, we provide a unique calibration document that notes this information, specific to the device. See an example of this document
What are the power and output of each LED, and the LED array as a whole?
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48-Position LED Arrays for TCR

U.S. Patent No. 11,458,447 Made specifically for use with Temperature Controlled Reactor (TCR).

96-Position, Single Wavelength LED Arrays

U.S. Patent No. 11,458,447 Use with Para-dox® Standard 96-Position Aluminum Reaction Blocks for photoredox catalysis applications.

96-Position Discovery LED Arrays

U.S. Patent No. 11,458,447 Lumidox® II Discovery LED Arrays for screening offer researchers an economical and time-saving way to evaluate all of the wavelengths that the...

24-Position, 18mm Spacing LED Arrays

U.S. Patent No. 11,458,447 Use with Para-dox® 24-Position Aluminum Reaction Blocks with 18mm Spacing for photoredox catalysis applications.

24-Position, 9mm Spacing LED Arrays

U.S. Patent No. 11,458,447 Use with Para-dox® 24-Position Aluminum Reaction Blocks with 9mm Spacing for photoredox catalysis applications, or HTe-Chem Assemblies for...

PCR Plate Adapters

If your workflow involves the use PCR plates, then Lumidox® II Lens Mat Arrays are perfectly suited for your research. Lumidox II Arrays generate highly precise,...

Cell Culture Plate Adapters

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Adapters for Gen I Arrays

Lumidox Generation I arrays are backwards compatible with Generation II controllers via the use of an adapter.